CANCER TYPE-SPECIFIC GENE PANELS FOR HEMATOLOGICAL MALIGNANCY

Many hematological malignancies share some recurrent genetic alterations, but most mutations are specific to a particular cancer type. The presence or absence of these gene changes may provide clinically relevant information regarding prognosis, resistance to certain therapies, and detection of disease recurrence.

We offer a range of genomic tests specifically designed for the unique types of hematological malignancies to offer patients an in-depth analysis of their disease, informing potential treatment plans for the best possible outcomes and providing peace of mind by monitoring for any possible recurrence.

LYMPH™

B AND T CELL LYMPHOMAS

Analysis of mutations in 121 key genes in B cell lymphoma and 103 key genes in T cell lymphoma by targeted DNA sequencing, alone or in combination with whole transcriptome mRNA sequencing

LEUMYE™

MYELOID NEOPLASMS

Analysis of mutations in 140 key genes in myeloid neoplasms by targeted DNA sequencing, alone or in combination with whole transcriptome mRNA sequencing

ALLEU™

ACUTE LYMPHOBLASTIC LEUKEMIA

Analysis of mutations and selected translocations of 95 key genes in ALL by targeted DNA sequencing in combination with whole transcriptome mRNA sequencing

LYMPH™

Comprehensive genomic profiling for B Cell and T Cell lymphoma 

Lymph™ analyses mutations and selected translocations in 121 key genes in B cell lymphoma and 103 key genes in T cell lymphoma by targeted DNA-sequencing (Lymph™–B/T D), or in combination with whole transcriptome mRNA sequencing (Lymph™–B/T DR) to detect a broader range of gene translocations and expression changes.

WHO IS IT FOR

LYMPH™ B D/DR

Patients with B cell lymphoma 

LYMPH™ T D/DR

Patients with

  • T lymphoblastic lymphoma (TLL)
  • Angioimmunoblastic T cell lymphoma (AITL)
  • Extranodal NK/T cell lymphoma (nasal type) (ENKTCL-NT)
  • Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS)
  • Anaplastic large cell lymphoma (ALCL) 

 

SAMPLE TYPES
Icon Tumour Tissue

Tumor tissue (FFPE block/slides, or frozen tissue)

Icon Fine Needle Biopsy

Fine needle biopsy

Icon Liquid Biopsy

Liquid biopsy (plasma and cerebrospinal fluid)

Peripheral blood or bone marrow  

LEUMYE™

Comprehensive genomic profiling for myeloid neoplasms

Leumye™ analyses mutations and selected translocations in 140 key genes in myeloid neoplasm by targeted DNA sequencing (Leumye™ D), or in combination with whole transcriptome mRNA sequencing (Leumye™ DR) to detect a broader range of gene translocations and expression changes.

WHO IS IT FOR

All patients with myeloid neoplasms

  • Acute myeloid leukemia (AML) and related neoplasms
  • Myelodysplastic syndromes (MDS)
  • Myeloproliferative neoplasms (MPN)
  • MDS/MPN
SAMPLE TYPE

Peripheral blood or bone marrow  

ALLEU™

Comprehensive genetic profiling for acute lymphoblastic leukemia (ALL) 

ALLEU™ analyses mutations and selected translocations of 95 key genes targeted DNA sequencing in ALL with whole transcriptome sequencing to detect various ALL-related gene fusions, including all BCR~ABL1 fusions and other common fusions in Ph-like ALL. This process assists with disease diagnosis and classification. It also assesses genetic predisposition to hereditary leukemia.

WHO IS IT FOR

Patients with ALL

SAMPLE TYPE

Peripheral blood or bone marrow  

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